Our Papers and Reviews
In Vitro Mechanical Stimulation to Reproduce the Pathological Hallmarks of Human Cardiac Fibrosis on A Beating Chip and Predict The Efficacy of Drugs and Advanced Therapies
Roberta Visone, Camilla Paoletti, Alessandro Cordiale, Letizia Nicoletti, Carla Divieto, Marco Rasponi, Valeria Chiono, Paola Occhetta
Advanced Healthcare Materials, Nov 2023
LivHeart: A Multi Organ-on-Chip Platform to Study Off-Target Cardiotoxicity of Drugs Upon Liver Metabolism
Erika Ferrari, Roberta Visone, Elisa Monti, Enrica Torretta, Matteo Moretti, Paola Occhetta, Marco Rasponi.
Advanced Materials Technologies, Jan 2023
Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform
Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, Massimo Walter Rivolta, Enrico Pesenti, Alberto Redaelli, Roberto Sassi, Marco Rasponi and Paola Occhetta
Toxicological Sciences, Oct 2022
doi.org/10.1093/toxsci/kfac108
Current strategies of mechanical stimulation for maturation of cardiac microtissues
Maria Carlos-Oliveira M., Lozano-Juan F., Occhetta P., & Visone R., Rasponi M.
Biophysical Reviews, Sept 2021
doi: 10.1007/s12551-021-00841-6
Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip.
Visone R., Ugolini G. S., Cruz-Moreira D., Marzorati S., Piazza S., Pesenti E., Redaelli A., Moretti M., Occhetta P. and Rasponi M.
Biofabrication , Feb 2021
doi: 10.1088/1758-5090/abe4c4
Hyperphysiological compression of articular cartilage induces an osteoarthritic phenotype in a cartilage-on-a-chip model.
Occhetta P, Mainardi A, Votta E, Vallmajo-Martin Q, Ehrbar M, Martin I, Barbero A, Rasponi M.
Nat Biomedical Engineering, Jul 2019
doi: 10.1038/s41551-019-0406-3.
A microscale biomimetic platform for generation and electro-mechanical stimulation of 3D cardiac microtissues.
Visone R, Talò G, Occhetta P, Cruz-Moreira D, Lopa S, Pappalardo OA, Redaelli A, Moretti M, Rasponi M.
APL Bioengineering , Oct 2018
doi: 10.1063/1.5037968.
A three-dimensional in vitro dynamic micro-tissue model of cardiac scar formation.
Occhetta P, Isu G, Lemme M, Conficconi C, Oertle P, Räz C, Visone R, Cerino G, Plodinec M, Rasponi M, Marsano A.
Integr Biol (Camb), March 2018
doi: 10.1039/c7ib00199a
Beating heart on a chip: a novel microfluidic platform to generate functional 3D cardiac microtissues.
Marsano A, Conficconi C, Lemme M, Occhetta P, Gaudiello E, Votta E, Cerino G, Redaelli A, Rasponi M.
Lab on a Chip, Feb 2016
doi: 10.1039/C5LC01356A